Back to Genetic Factors Guide

Upload your DNA raw data file to automatically scan for histamine, MCAS, and hEDS/HSD-related genetic variants. This tool checks multiple key single nucleotide polymorphisms (SNPs) across several categories and shows you which variants you carry, along with your specific genotypes. All processing happens locally in your browser—your DNA data never leaves your device.

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How to Get Your DNA Raw Data File

🧬23andMe

  1. Log in to your 23andMe account
  2. Go to Tools → Browse Raw Data
  3. Click "Download" at the top of the page
  4. Select "All DNA" or "Ancestry"
  5. Choose "Download Raw Data"
  6. Enter your password to confirm
  7. Wait for the email with your download link (usually arrives within minutes)
  8. Download the .txt file to your computer

Note: The file will be named something like "genome_YourName_v5_Full_YYYYMMDD.txt"

🌳AncestryDNA

  1. Log in to your Ancestry account
  2. Go to DNA → Your DNA Results Summary
  3. Click on "Settings" (gear icon)
  4. Scroll down to "Actions" section
  5. Click "Download Raw DNA Data"
  6. Enter your password to confirm
  7. Check your email for the download link
  8. Download the .txt file to your computer

Note: The file will be named something like "AncestryDNA.txt" or "Ancestry_dna_file_YYYYMMDD.txt"

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Important Notes:

  • Make sure you download the raw data file, not a report or summary
  • The file should be a .txt file (text format)
  • File sizes are typically 5-50MB
  • If you have multiple DNA tests, use the most recent one
  • Processing happens entirely in your browser—your data never leaves your device
  • This tool does not replace medical-grade genetic testing, which is more accurate and comprehensive. Consult with qualified healthcare professionals for clinical genetic testing.

Want to Learn More About These Genetic Variants?

Visit our comprehensive guide to understand what each genetic variant means, how it affects histamine metabolism, and what you can do about it.

View Complete Genetic Factors Guide

Sources and Review

Editorial reviewed

Author: Gadolinium.org Editorial Team (Patient-Led Education)

Last reviewed: February 21, 2026

How this page was reviewed: This tool reports variants from a consumer DNA file you upload. Consumer genotyping is not clinical-grade testing, and the variant interpretations reflect community discussion rather than diagnostic criteria.

Clinician review: No physician has reviewed this page. It was checked by the editorial team against the sources listed below.

This page is for education only and is not a diagnosis or treatment plan.